It is not if white has the 1st nove, but who has the 1st

[Chessqueen]

Even if you force Black to have he 1st move computer engines still use openings and whichever side has the first move has the advantage even if Black move first:

[Event "Computer chess game"]
[Site "DESKTOP-OFQ3C0P"]
[Date "2018.11.10"]
[Round "?"]
[White "Stockfish_9_x64"]
[Black "Stockfish_9_x64"]
[Result "*"]
[BlackElo "2000"]
[Time "22:34:44"]
[WhiteElo "2000"]
[TimeControl "40/120:0"]
[SetUp "1"]
[FEN "rnbqkbnr/pppppppp/8/8/8/8/PPPPPPPP/RNBQKBNR b Kk - 0 1"]
[Termination "unterminated"]
[PlyCount "22"]
[WhiteType "program"]
[BlackType "program"]

1. ... e5 {(e7-e5 e2-e4 Ng8-f6 Nb1-c3 Bf8-b4 a2-a3 Bb4xc3 d2xc3 O-O Ng1-f3
d7-d6 Qd1-d3 Bc8-e6 Bc1-e3 Nf6-g4 Bf1-e2 Ng4xe3 Qd3xe3 Nb8-d7 O-O) +0.41/17
3} 2. e4 {(e2-e4 Ng8-f6 Ng1-f3 Nf6xe4 d2-d3 Ne4-f6 Nf3xe5 Nb8-c6 Ne5xc6
d7xc6 Bf1-e2 Bf8-e7 Nb1-c3 O-O O-O Rf8-e8 h2-h3 Be7-d6 d3-d4 Nf6-d5 Nc3xd5
c6xd5 Bc1-e3) -0.12/17 2} Nf6 {(Ng8-f6 Nb1-c3 Bf8-c5 Ng1-f3 d7-d5 e4xd5 O-O
Bf1-e2 e5-e4 Nf3-e5 Rf8-e8 d2-d4 e4xd3/ep Ne5xd3 Bc5-b6 O-O Nf6xd5 Be2-f3
Nd5xc3 b2xc3 Nb8-c6) +0.41/17 1} 3. Nc3 {(Nb1-c3 Bf8-b4 Ng1-f3 O-O Bf1-c4
c7-c6 a2-a3 Bb4-a5 Nf3xe5 d7-d5 e4xd5 c6xd5 Bc4-b5 d5-d4 Nc3-a4 Nb8-c6
Bb5xc6) -0.25/17 3} Bb4 {(Bf8-b4 Ng1-f3 O-O Bf1-e2 Bb4xc3 d2xc3 d7-d6
Bc1-g5 h7-h6 Bg5xf6 Qd8xf6 Be2-c4 Nb8-d7 Qd1-e2 Nd7-c5 O-O Bc8-d7) +0.78/15
1} 4. Nf3 {(Ng1-f3 O-O Bf1-e2 Nb8-c6 d2-d3 d7-d5 e4xd5 Nf6xd5 Bc1-d2 Nd5xc3
b2xc3 Bb4-e7 O-O Bc8-f5 Ra1-b1 Ra8-b8 Rf1-e1 h7-h6 Be2-f1 f7-f6 c3-c4
Qd8-d6 Bd2-c3) -0.24/19 5} O-O {(O-O Bf1-e2 Nb8-c6 d2-d3 d7-d5 e4xd5 Nf6xd5
Bc1-d2 Nd5xc3 b2xc3 Bb4-c5 O-O b7-b6 d3-d4 e5xd4 c3xd4 Bc5xd4 Nf3xd4 Nc6xd4
Be2-d3 f7-f5 Rf1-e1 Bc8-b7 Qd1-h5 c7-c5) +0.60/17 1} 5. Nxe5 {(Nf3xe5 d7-d5
Bf1-e2 Qd8-e7 Ne5-d3 Bb4xc3 b2xc3 d5xe4 Nd3-f4 c7-c5 O-O Rf8-d8 d2-d3
Nb8-c6 c3-c4 Nc6-e5 Bc1-d2 g7-g5 Nf4-h5 Nf6xh5 Be2xh5 e4xd3 c2xd3 Rd8xd3
Qd1-c1) -0.12/20 9} d5 {(d7-d5 Bf1-e2 d5-d4 Ne5-d3 Nb8-c6 e4-e5 Nf6-d7
Nc3-e4 Nd7xe5 Nd3xb4 Nc6xb4 d2-d3 f7-f5 Ne4-d2 Bc8-e6 Nd2-f3 Ne5xf3+ Be2xf3
Be6-d5 Bf3xd5+ Nb4xd5 O-O Qd8-d6 Rf1-e1 c7-c6 Bc1-d2) +0.27/17 0} 6. Be2
{(Bf1-e2 d5-d4 Ne5-d3 Nb8-c6 e4-e5 Nf6-d7 Nc3-e4 Nd7xe5 Nd3xb4 Nc6xb4 d2-d3
f7-f5 Ne4-d2 Bc8-e6 O-O Nb4xa2 Nd2-f3 Na2xc1 Nf3xe5 Nc1xe2+ Qd1xe2 c7-c5
Rf1-e1 Rf8-e8 c2-c3 b7-b6) -0.20/20 3} d4 {(d5-d4 Ne5-d3 Nb8-c6 Nd3xb4
Nc6xb4 a2-a3 Nb4-c6 Nc3-a2 Nf6xe4 d2-d3 Ne4-c5 Bc1-f4 f7-f6 O-O a7-a5
Be2-f3 Nc6-e5 Rf1-e1 Ne5xf3+ Qd1xf3 c7-c6 Ra1-b1) +0.31/18 1} 7. Nd3
{(Ne5-d3 Nb8-c6 Nd3xb4 Nc6xb4 a2-a3 Nb4-c6 Nc3-a2 Nf6xe4 d2-d3 Ne4-d6 O-O
Rf8-e8 Bc1-f4 Qd8-f6 Bf4-g3 Nc6-e5 c2-c3 Nd6-f5 Bg3xe5 Re8xe5 Be2-f3 c7-c5
Bf3-e4 Nf5-d6 Be4-f3 d4xc3) 0.00/19 2} Nc6 {(Nb8-c6 Nd3xb4 Nc6xb4 a2-a3
Nb4-c6 Nc3-b1 Nf6xe4 d2-d3 Ne4-c5 O-O Rf8-e8 Rf1-e1 Qd8-e7 Nb1-d2 Bc8-g4
Nd2-e4 Bg4xe2 Re1xe2 Nc5-e6 Bc1-d2 Ra8-d8 Re2-e1 h7-h6 Qd1-f3) +0.11/19 2}
8. Nxb4 {(Nd3xb4 Nc6xb4 a2-a3 Nb4-c6 Nc3-b1 Nf6xe4 d2-d3 Ne4-c5 O-O Rf8-e8
Be2-f3 Nc6-e5 Bc1-f4 Ne5xf3+ Qd1xf3 Bc8-d7 Nb1-d2 g7-g5 Bf4-g3 Bd7-c6
Qf3-g4 b7-b6 Ra1-e1) +0.26/18 1} Nxb4 {(Nc6xb4 a2-a3 Nb4-c6 Nc3-b1 Nf6xe4
d2-d3 Ne4-c5 O-O Rf8-e8 Bc1-f4 Nc5-a4 b2-b3 Na4-b6 Be2-f3 Bc8-e6 Bf3xc6
b7xc6 Nb1-d2 Nb6-d5 Qd1-f3 c6-c5 Nd2-e4 Nd5xf4 Qf3xf4 Qd8-e7 Rf1-e1 Be6-d5
h2-h3 f7-f6 Qf4-g3) +0.10/21 2} 9. a3 {(a2-a3 Nb4-c6 Nc3-b1 Nf6xe4 d2-d3
Ne4-f6 O-O Rf8-e8 Bc1-f4 Nc6-e5 Bf4xe5 Re8xe5 Nb1-d2 c7-c5 Be2-f3 Qd8-c7
Nd2-e4 Nf6xe4 Bf3xe4 Bc8-f5 f2-f4 Re5xe4 d3xe4 Bf5xe4 f4-f5) +0.24/20 1}
Nc6 {(Nb4-c6 Nc3-b1 Nf6xe4 d2-d3 Ne4-f6 O-O Nf6-d5 Rf1-e1 Rf8-e8 Nb1-d2
Bc8-f5 Nd2-f1 Nc6-e5 Bc1-d2 Qd8-d7 Nf1-g3 Ra8-d8 Ng3xf5 Qd7xf5 g2-g4 Qf5-c8
f2-f4 Ne5-g6 f4-f5 Ng6-h4) +0.19/19 1} 10. Nb1 {(Nc3-b1 Nf6xe4 d2-d3 Ne4-f6
O-O Rf8-e8 Rf1-e1 Nf6-d5 Nb1-d2 h7-h6 Nd2-e4 b7-b6 Bc1-d2 Nc6-e5 c2-c4
d4xc3/ep Ne4xc3 Nd5-f6 d3-d4 Qd8xd4 Nc3-b5) +0.14/18 2} Nxe4 {(Nf6xe4 d2-d3
Ne4-f6 O-O Nf6-d5 Nb1-d2 b7-b6 Rf1-e1 Bc8-b7 Nd2-e4 Qd8-d7 Be2-h5 Ra8-e8
c2-c4 Nd5-e7 Bc1-f4 Ne7-g6 Bh5xg6 f7xg6 Bf4-g3 Nc6-e5) +0.22/19 0} 11. d3
{(d2-d3 Ne4-f6 O-O Rf8-e8 Bc1-f4 Nc6-e5 Nb1-d2 c7-c5 Bf4-g5 h7-h6 Bg5xf6
Qd8xf6 f2-f4 Ne5-g6 Nd2-e4 Qf6-c6 f4-f5 Ng6-h4 f5-f6 Bc8-f5) +0.14/19 1}
Nf6 {(Ne4-f6 O-O Nc6-e5 Bc1-g5 h7-h6 Bg5xf6 Qd8xf6 Nb1-d2 Rf8-e8 f2-f4
Ne5-d7 Be2-g4 Qf6-d8 Qd1-f3 Nd7-f6 Bg4xc8 Ra8xc8 Ra1-e1 Qd8-d5 Qf3xd5
Nf6xd5) +0.03/19 2} 12. O-O {(O-O) +0.19/21 3} *